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A study comparing individuals with insomnia to healthy sleepers found significantly lower glutathione peroxidase activity in the insomnia group

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The proposed mechanisms include upregulation of growth hormone receptors in fibroblasts, modulation of the nitric oxide (NO) system for enhanced angiogenesis (new blood vessel growth), and reduction of inflammatory cytokines

Woniak D, Drzymaa S, Przysawski J, Drzymaa-Czy S (2021) Dietary supplements in hypothyroidism

Poor Diet : Deficiencies in essential nutrients can impair synthesis